When ace high school detective Jimmy Kudo is fed a mysterious substance by a pair of nefarious men in black--poof! He is physically transformed into a first grader. Until Jimmy can find a cure for his miniature malady, he takes on the pseudonym Conan Edogawa and continues to solve all the cases that come his way.

The death of a private detective puts Conan back on the trail of the mysterious Syndicate. Now he believes he's identified one of the Men in Black--or, rather, a Woman in Black--as American actress Chris Vineyard. But could the elusive mistress of disguise be closer than Conan realizes? When Conan and Harley Hartwell investigate a suicide in the apartment building of daffy English teacher Jodie Santemillion, they discover more than just foul play. Who is Miss Jodie?